The Reds will welcome the French side to Anfield at 8 p.m. GMT for their seventh match of the new league phase.
Arne Slot’s men have a perfect record in the competition since the start of the season with six consecutive victories, are three points clear at the top of the table and are certain of at least one place in the elimination phase.
Avoiding defeat to Lille would confirm a top-eight finish for Liverpool and automatic progression to the last 16.
Further results could also see the Reds qualify for the last 16, even if they lose to Lille, with only 11 of the other 35 clubs now mathematically able to put them back in the table with two matches remaining.
Slot’s team will also travel to the Netherlands to face PSV Eindhoven on January 29 in their final outing of the league stage.
-The clubs ranked ninth to 24th in the final ranking will compete in two-way play-offs to reach the last 16. Players who finish 25th or lower are eliminated from European competition for 2024-25
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The knockout play-offs are scheduled for February 11-12 and February 18-19, before the last 16 ties on March 4-5 and March 11-12.
