hope – Researchers from CNRS and Grenoble Alpes University have just found a molecule that can block the progression of the disease in mice affected at an early stage of Alzheimer’s disease
“An astonishing discovery. » Researchers from CNRS and Grenoble Alpes University have just found a molecule to protect the brains of mice from Alzheimer’s disease. Enough to raise hope for the million people suffering from this neurodegenerative disease in France and their loved ones.
What does this molecule consist of? How can we explain its effectiveness? And above all, could it be transposed to humans? Marc Dhenain, research director at CNRS whose team worked with that of Alain Buisson, professor at Grenoble Alpes University, explains everything to us.
What does this molecule consist of?
Alzheimer’s patients have an abnormal accumulation of two proteins, amyloid-β and Tau, in their brain. These cause lesions which will alter neurons and their synapses, ultimately leading to memory loss. “We think that in Alzheimer’s disease, the process by which amyloid proteins function is the same as Prions,” explains Marc Dhenain. In Prion diseases, such as mad cow disease or Creutzfeldt-Jakob disease, the patient has a Prion protein in his brain that changes shape. “When it changes shape, it(…) Read more on 20minutes
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