What conclusions for the Barrier-Protect study

Live from the Heart Rhythm 2024 conference

The use of antibacterial adhesive films impregnated with iodine reduces the risk of infection of implantable rhythm prostheses.

Key messages

The use of antibacterial adhesive films impregnated with iodine was associated with:

  • 2 times fewer positive samples in the lodge
  • Less infection of implantable rhythm prosthesis

After the antibacterial envelope, here is a new tool in the arsenal for the prevention of infections of implantable rhythm prostheses.

Introduction

Implantable cardiac device infection is a common post-implantation complication and is associated with excess mortality.

There are no current studies that have evaluated the usefulness of iodine-impregnated antibacterial adhesive films in reducing these infections.

Methodology and results

Population

384 patients undergoing a change of pacemaker or defibrillator box.

Design

Randomized controlled trial, antibacterial adhesive film impregnated with iodine versus no film.

Primary endpoint

Positive bacteriological sample from the compartment taken at the end of the procedure.

Main result

The compartment swab was positive in 11% of cases in the antibacterial adhesive film group impregnated with iodine vs. 21% in the no film group.

Secondary endpoint results

0 infections were recorded in the antibacterial adhesive film group impregnated with iodine vs. 4 in the no film group.

Figure 2

Conclusion

The use of antibacterial adhesive film impregnated with iodine during changes of implantable rhythmic prosthesis boxes was associated with fewer positive bacteriological samples from the compartment and less infection.

Antibacterial adhesive films impregnated with iodine are inexpensive compared to the antibacterial envelopes currently available on the market and constitute a new tool that is easy to implement in our practice to reduce the risk of infection of implantable rhythm prostheses.

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