The objective of the research was therefore to evaluate a possible interaction between body weight or BMI and the prognosis and recurrence of hormone receptor-positive breast cancer. Research does indeed highlight patterns of weight gain in women with early-stage HR+ breast cancer.
Obesity is known to be associated with an increased risk of developing certain types of cancer, including breast cancer. Obese women are also twice as likely to die from breast cancer as those without it.
Persistent ethnic health disparities are also implicated in trends in breast cancer and obesity. Thus, among women with early-stage breast cancer, black women have higher rates of obesity and obesity-related comorbidities (such as hypertension, heart disease, and diabetes). than white women. Black women also have a 40% higher breast cancer mortality rate than white women, and a mortality rate more than 2 times that of their Asian counterparts.
The study aims to characterize changes in body mass index (BMI) over time in hormone receptor (HR)-positive breast cancer survivors and to examine whether BMI and these ethnic disparities may be factors predictive of recidivism. The analysis highlights:
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weight gain patterns in early-stage HR+ breast cancer patients;
- This tendency towards weight prose is observed just as much in women at a healthy weight as in overweight ones.
- especially in people who had a healthy BMI or were overweight at the time of diagnosis.
Initial observations which call for better understand the impact of excess adiposity on the outcomes of breast cancer patients.
