What is special about these super powerful drugs?

What is special about these super powerful drugs?
What is special about these super powerful drugs?

The American authorities have issued an alert due to an increasing circulation of these new synthetic opioids. Some overdose outbreaks have been located in France. What do we know about these products and their dangers?

They are up to 500 times stronger than morphine, and potentially more dangerous than fentanyl in the United States: nitazenes are a family of powerful synthetic opioids that have come into the crosshairs of the authorities due to their increasing circulation in North America (Canada, United States), but also in Europe. In a report published on Wednesday, June 26, the United Nations Office on Drugs and Crime (UNODC) points out a “increase in overdose deaths” linked to these substances in high-income countries. Do these synthetic opioids threaten France?

A pharmacological power

In this family of ultra-potent drugs, isotonitazene is 250 times stronger than heroin and 500 times stronger than morphine. That’s not all: metonitazene, protonitazene or even etonitazene are respectively 50, 100 and 500 times more powerful than heroin, according to a study published in January 2024 in The Lancet Public Health. Synthesized as an alternative…

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