Aston Villa boss Unai Emery makes three changes to the side that drew 2-2 against Crystal Palace on Saturday.
In come Matty Cash, Lucas Digne and Boubacar Kamara while Ross Barkley, Ian Maatsen and Lamare Bogarde drop to the bench.
Kamara comes in after recovering from a hamstring injury while Ezri Konsa is on the bench following a hip injury.
Jhon Duran has scored in each of his two home Champions League appearances for Aston Villa this season and could make an impact from the bench once again.
Aston Villa XI: Martinez, Carlos, Torres, Cash, Digne, Tielemans, Bailey, Rogers, McGinn, Watkins
Subs: Olsen, Gauci, Bogarde, Maatsen, Konsa, Mings, Buendia, Barkley, Duran, Philogene, Nedeljkovic,
Juventus boss Thiago Motta makes just one change from the side that drew 0-0 at AC Milan in Serie A on Saturday.
Timothy Weah steps in for the injured Weston McKennie while former Villa midfielder Douglas Luiz is absent from the squad along with striker Dusan Vlahovic.
They name just four outfield players on the bench as they continue to battle an injury crisis.
Juventus XI: Di Gregorio, Savona, Kalulu, Gatti, Cambiaso, Locatelli, Thuram, Conceicao, Yildiz, Koopmeiners, Weah
Subs: Perin, Danilo, Fagioli, Pinsoglio, Rouhi, Mbangula
