Club Bruges, 27th in the Champions League standings, have ex-Sunderland and Liverpool keeper Simon Mignolet in goal, while former Norwich forward Christos Tzolis also starts.
Club Brugge XI: Mignolet, De Cuyper, Mechele, Ordonez, Seys, Jashari, Vanaken, Nielsen, Tzolis, Jutgla, Skov Olsen.
Subs: Jackers, Siquet, Spileers, Sabbe, Romero, Meijer, Vetlesen, Vermant, Skoras, Talbi.
Defender Tyrone Mings, who was out of action for 14 months because of an anterior cruciate ligament injury between August 2023 and October 2024, makes his Champions League debut.
He is one of five changes to the Aston Villa starting 11 from the side that lost 4-1 at Tottenham, with starts too for Ian Maatsen, Diego Carlos, Boubacar Kamara and Leon Bailey.
Aston Villa XI: Martinez, Maatsen, Konsa, Carlos, Mings, Kamara, Tielemans, Bailey, Rogers, McGinn, Watkins.
Subs: Gauci, Digne, Torres, Bogarde, Nedeljkovic, Onana, Buendia, Ramsey, Swinkels, Philogene, Duran