According to research, people taking High doses of Adderall are five times more likely to develop psychotic or manic episodes. The finding, published by Science Alert, adds to concerns already raised by the FDA in the early 2000s, which added a warning to the drug.
The study, led by psychiatrist Lauren Moran, looked at medical records of patients aged 16 to 35 hospitalized between 2005 and 2019. She showed that Those taking Adderall were 2.68 times more likely to be admitted for psychotic disorders than those not taking itand this risk increased significantly for doses greater than 40 mg per day.
Unlike Adderall, Another ADHD treatment, Ritalin, has not shown such effects. According to researchers, this is explained by the distinct mechanisms of action of the two drugs: Adderall increases the release of dopamine, while Ritalin prevents its reabsorption.
Lauren Moran stresses the need to better regulate prescriptions, calling for strict indication of maximum doses on packaging. She denounces “negligence in prescribing doses,” noting that some clinicians try to eliminate all ADHD symptoms, which is unrealistic.
In the United States, Adderall can be prescribed via teleconsultation,…
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