Winner 6-4, 7-5, 4-6, 7-6 (7/4), the native of Atlanta (Georgia) will face in the semi-finals the winner of the match between the defending champion Jannik Sinner (1st) and the Australian Alex de Minaur (8th), scheduled for later in the evening in Melbourne.
By dominating Sonego on Wednesday on the court of the Rod Laver Arena, Shelton offered himself at 22 his second semi-final in the major tournaments, after that of 2023 at the US Open.
The 29-year-old Italian was playing his first Grand Slam quarter-final. Winner of the last duel against Shelton in the first round of Roland-Garros in 2023, he is now trailing 2-1 in his direct confrontations with the American left-hander, after having lost in 2022 in Cincinnati, already on hard court.
Sonego, however, offered a long resistance to Shelton, who took almost four hours to defeat him.