Whether with or without oxygen, living organisms need energy to function. This is produced through different types of reactions and we observe similarities between organisms from a molecular point of view.
One of these molecules is of particular interest to a team from the Translational Research and Innovation in Medicine and Complexity laboratory: ubiquinone, known by its trade name coenzyme Q10. If there is a dysfunction in the synthesis of ubiquinone, this can lead to serious diseases in humans.
One of the projects was interested in the evolution through the ages of the molecules which synthesize this molecule, while the other sought to understand the origin of the three oxygen atoms which compose it, in an environment which does not does not contain any.
These multidisciplinary studies have enabled significant scientific advances, which could contribute in the longer term to the development of new anti-bacterial drugs or even to the synthesis of molecules of biotechnological interest.
To find out more about the O2-taboo and dEEPEN projects, don’t hesitate to discover the episode of the Focus sciences series dedicated to it! ???? Understanding the extremely small on extremely large time scales.
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RFind all the videos from the Alps delegation on our CNRS Alpes YouTube channel.
To find out more about:
– the CNRS Alps delegation
– the Translational Research and Innovation in Medicine and Complexity Laboratory (TIMC – CNRS / UGA / VetAgro Sup / Grenoble INP – UGA)
– the Translational microbiology – Evolution – Engineering team
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This research and this episode of Focus sciences were funded in whole or in part by the National Research Agency.
Illustration credit: Kam Production
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