According to a press release from Marseille university hospitals relayed by Midi Libre, Friday January 17, a patient suffering from HIV is said to be in remission. This would be a first in France and the eighth case in the world.
This would be a major medical breakthrough. As reported by Midi Libre, Friday January 17, a woman was declared in remission from HIV in Marseille, after 25 years of fighting the disease. This patient, followed by the Human Immunodeficiency Information and Care Center (CISIH) at Sainte-Marguerite Hospital in the Marseille city, “could represent the first case of remission of functional cure of HIV in France after an allogeneic bone marrow transplant“, explains a press release from the university hospitals of Marseille, relayed by our colleagues.
HIV positive since 1999, the patient is now 60 years old. “Despite effective antiretroviral treatments from 2010, she developed acute myeloid leukemia in 2020. An allogeneic bone marrow transplant carried out at the Paoli-Calmettes Institute in July 2020 made it possible to treat his leukemia. The donor had a rare genetic mutation (Delta 32) in the CCR5 gene, preventing HIV from entering cells“, details the press release.
Only seven cases of HIV cure in the world
After this transplant, the patient continued antiretroviral treatment for three years before stopping in October 2023. The virological tests subsequently taken by the patient were negative. Curing HIV would be a first in France. Globally, only seven cases of functional cure of HIV after allogeneic bone marrow transplantation, aimed at treating lymphoma or leukemia, have been reported worldwide. For six of them, the donor carried the Delta 32 mutation on the CCR5 receptor.
-published on January 17 at 5:12 p.m., Quentin Marchal, 6Medias
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