A study proves the link between the appearance of psychiatric disorders and Covid-19 in its severe forms.
Clinical and biological markers have been identified as predictive indicators of these disorders.
The link between severe manifestations of Covid-19 requiring hospitalization and the onset of psychiatric disorders in patients has just been proven by a study published in Molecular Psychiatry.
This was carried out between January 2020 and September 2022 using data from nearly 35,000 patients without a psychiatric history from AP-HP hospitals. Researchers from the Moods team at Inserm and Paris-Saclay were able to prove that 10.8% of them developed a recent-onset disorder.
Clinical and biological markers to identify
Data show that some clinical and biological markers indicating severity of Covid-19 are present in patients who develop a psychiatric disorder up to two years and nine months after hospitalization.
The study findings suggest that a hospital stay of more than seven days during which the patient experiences acute delirium, an elevated monocyte count and an elevated inflammatory marker (CRP) predict recent-onset psychiatric disorders post-Covid.
Predictive scores based on these markers have good positive predictive values at 12 months. This is up to 7.5 times more accurate than random scores in women under 65, according to this study by the team of researchers from the Kremlin-Bicêtre hospital.
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