This new blood test could detect osteoarthritis of the knees up to 8 years in advance

This new blood test could detect osteoarthritis of the knees up to 8 years in advance
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Osteoarthritis, this joint disease which leads to the destruction of cartilage, affects nearly 528 million people worldwide, including 10 million French people. Generally, it is only detected after significant structural damage is observed at the joint. Faced with this problem, a team of English researchers has developed a blood treatment to diagnose the progression of osteoarthritis of the knees up to 8 years in advance.

The journal Science Advances has revealed the beginnings of a scientific revolution: a blood test to detect knee osteoarthritis. To propose this new examination, the researchers looked at 24 predictive biomarkers responsible for knee osteoarthritis on a panel of 200 women. They discovered, by isolating these different molecules in the blood, that 6 of them can indicate with 77% reliability whether a person will develop osteoarthritis of the knee in the following eight years. Thus, if this discovery is confirmed, it would firstly make it possible to predict the disease early and anticipate the creation of potential treatments to slow its progression.

These blood tests have also proven to be more effective than traditional approaches based on age, body weight or knee pain, emphasize the authors of the study. According to the researchers, this effectiveness is explained by the ability of biomarkers to detect subtle molecular changes (…)

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