Inter centre-back Stefan De Vrij has recovered from injury and is expected to be back in his side's starting XI as the Nerazzurri travel to Cagliari.
Kick-off will be at 6:00 p.m. CET (5:00 p.m. GMT) at the Unipol Domus in Cagliari.
Simone Inzaghi will still be without Matteo Darmian in defense, meaning Yann Bisseck will retain his place in the bottom three, with Denzel Dumfries deployed further forward as a right-back.
LEVERKUSEN, GERMANY – DECEMBER 10: Hakan Calhanoglu of FC Internazionale shoots under pressure from Exequiel Palacios of Bayer 04 Leverkusen during the MD6 match of the 2024/25 UEFA Champions League league stage between Bayer 04 Leverkusen and FC Internazionale Milano at BayArena on December 10. , 2024 in Leverkusen, Germany. (Photo by Lars Baron/Getty Images)
The same will apply to the attacking duo, with Lautaro Martinez set to get the nod alongside Marcus Thuram in the hope of ending their four-game Serie A drought.
Cagliari coach Davide Nicola is expected to welcome Yerry Mina back into his four-man defensive line, while full-backs Nadir Zortea and Tommaso Augello could be used as attacking wingers alongside Nicolas Viola.
The match will be available to watch and stream live via TNT Sports 2 and One Football in the UK. US fans can stream it live on Paramount+. DAZN holds the exclusive TV rights to the game in Italy. You can also follow every minute of the action on the Football Italia live blog.
CAGLIARI, ITALY – OCTOBER 20: Nicolas Viola of Cagliari (not seen) scores his goal 1-0 during the Serie A match between Cagliari and Turin at Sardegna Arena on October 20, 2024 in Cagliari, Italy. (Photo by Enrico Locci/Getty Images)
Cagliari (4-2-3-1) : Sherri ; Zappa, Mina, Luperto, Obert; Makoumbou, Adopo; Zortea, Viola, Augello; Small.
Inter (3-5-2): Sommer; Bisseck, De Vrij, Bastoni; Dumfries, Barella, Calhanoglu, Mkhitaryan, Dimarco; Thuram, Lautaro Martínez.