Mikel Arteta has made just one change from the side that played Newcastle at the weekend, with Ben White returning to face Inter Milan.
After not starting our last two games, White comes back in at right back, with Jurrien Timber continuing at left back. Gabriel and William Saliba form the central defensive partnership.
Declan Rice misses out entirely with a foot injury so Thomas Partey reverts to midfield, with Mikel Merino and Leandro Trossard.
Kai Havertz starts up front with captain Bukayo Saka and Gabriel Martinelli on the flanks.
After missing our last 12 games with an ankle injury, Martin Odegaard is fit enough to return to the bench. Also among our subs are 18-year-old defender Josh Robinson and Nathan Butler-Oyedeji, a 21-year-old forward. Both are yet to represent the first-team.
The visitors make five changhes from the side that beat Venezia 1-0 at the weekend. Top scorer Lautaro Martinez starts up front but former Gunner Henrikh Mkhitaryan is on the bench, alongside Italy internationals Alessandro Bastoni and Nicolo Barella.
Arsenal: Raya, White, Saliba, Gabriel, Timber, Partey, Merino, Trossard, Saka, Martinelli, Havertz. Subs: Neto, Robinson, Zinchenko, Myles-Skelly, Kiwior, Jorginho, Odegaard, Nwaneri, Sterling, Jesus, Butler-Oyedeji.
Inter: Sommer, Dumfries, Pavard, De Vrij, Bisseck, Darmian, Frattesi, Calhanoglu, Zielinski, Taremi, L Martinez. Subs: Di Gennaro, J Martinez, Arnautovic, Thuram, Acerbi, Buchanan, Asllani, Mkhitaryan, Barella, Dimarco, Bastoni.
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