It’s done ! For the first time, scientists have achieved the feat of regenerating a kidney. It is to a team from Singapore that we owe this feat which will change the daily lives of all those suffering from chronic kidney failure.
Late stage of chronic kidney disease (CKD), a silent and irreversible damage to the filtration function of the kidney favored (among others) by diabetes and hypertension, chronic renal failure is a disease which is characterized by the definitive destruction nephronsthese cells that filter blood and waste and produce urine.
It is estimated that when the kidney has lost 85% of its capacity (stage of renal failure), it can no longer fulfill its essential role and that it is then necessary to resort to a transplant (also called kidney transplantation). If the transplant is not possible, for various reasons, the patient then enters dialysis. Heavy treatments in all cases. Regenerating the kidney would restore the initial functions of the organthat’s a game changer.
A protein at the heart of the regeneration process
Teams from Singapore have succeeded in identifying an immunoregulatory protein capable of reversing “damage caused by acute and chronic kidney disease s” tells us the media intended for health professionals Sante Log which relays the study, published in the journal Nature Communications.
“France has nearly 100,000 people with kidney failure, more than half of whom are on dialysis (the others having benefited from a transplant). Under these conditions, the work of these researchers represents immense hope for patients.”, welcome the researchers.
Experimented on mice, this model is particularly interesting, because this protein precisely targets damaged cells.
“Our studies suggest potential therapeutic opportunities for anti-IL11 in acute and chronic kidney diseases”, conclude the researchers who carried out this work.
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