Some heart medications also protect against dementia

What if certain treatments for cardiovascular disease could also protect your brain? This is what a recent study by the Karolinska Institute (Sweden) suggests, published in Alzheimer’s & Dementia : The Journal of the Alzheimer’s Association : Prolonged use of medications for cardiovascular disorders could also reduce the risk of dementia in older people.

Risk of dementia reduced by up to 25%

By analyzing data from 88,000 people diagnosed with dementia between 2011 and 2016, compared to 880,000 individuals without dementia, researchers observed a significant correlation between long-term use (more than 5 years) of certain medications and a reduction in risk of dementia. The results show that antihypertensives, statins, diuretics and anticoagulants are associated with a risk reduction ranging from 4 to 25%.

“We see a clear link between prolonged use of these treatments and cognitive protection in old age”explain the scientists in a press release. Note that combinations of these drugs seem even more effective than their individual use and provide additional protection against dementia.

A reverse effect for certain treatments

The study, however, highlights a potential risk linked to the use of antiplatelets, often prescribed to prevent strokes. These medications may increase the risk of brain microbleeds, a factor associated with cognitive decline.
“These results highlight the need to better understand the underlying mechanisms,” underline the researchers, adding that randomized clinical studies will be essential to confirm these observations and explore new preventive avenues.

Although no cure yet exists for dementia, this research offers hope by identifying potential methods to delay its onset. In addition to medical treatments, adopting a healthy lifestyle and a balanced diet can also play a key role in protecting your brain and preventing the risk of dementia, the authors point out.