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GLP-1 analogues: prescription conditions restricted only for specialties indicated in obesity

aGLP-1

Indicated in the treatment of obesity

Indicated in type 2 diabetes

WEGOVY, SAXENDA

X

MOUNJARO

X

X

OZEMPIC, TRULICITY, VICTOZA, XULTOPHY, BYETTA

X

aGLP-1 indicated in the treatment of obesity

The initial prescription of aGLP-1 indicated in the treatment of obesity (WEGOVY, SAXENDA and MOUNJARO) must be carried out by a doctor specializing in endocrinology-diabetology-nutrition or competent in nutrition (i.e. holder of a DESC, an FST or a nutrition VAE). Renewals can be carried out by any doctor.

Doctors are also asked to comply with the HAS care pathway: prescribe aGLP-1 indicated in the treatment of obesity to patients with an initial body mass index (BMI) greater than or equal to 35 kg/m2aged under 65.

These medications should only be used as a second line, in the event of failure of nutritional support in combination with a hypocaloric diet and physical activity.

New aGLP-1, indicated in the treatment of obesity and type 2 diabetes

The drug MOUNJARO (tirzepatide) has been marketed since November 2024 in , at a price freely set by the laboratory (not reimbursed). Agonist of GLP-1 (glucagon-like peptide 1) and GIP (glucose-dependent insulinotropic polypeptide), it is indicated in the treatment of obesity and type 2 diabetes.

Whatever the indication, this medicine is subject to the restricted prescription and supply conditions for aGLP-1 indicated in the treatment of obesity.

aGLP-1 indicated only in type 2 diabetes

The other aGLP-1 available today in France and indicated in type 2 diabetes only (OZEMPIC, TRULICITY, VICTOZA, XULTOPHY and BYETTA) are not subject to these restricted prescription conditions.

Source: ANSM news from 08/10/2024, updated on 13/11/2024

Health

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