Ayahuasca against alcohol addiction? Volunteers invited to test hallucinogenic substance in London

Ayahuasca against alcohol addiction? Volunteers invited to test hallucinogenic substance in London
Ayahuasca against alcohol addiction? Volunteers invited to test hallucinogenic substance in London

One addiction versus another? University College London has just launched a surprising therapeutic trial to try to reduce problematic alcohol consumption.

According to The Guardian, experts are seeking evidence that dimethyltryptamine (DMT), a powerful psychedelic used in healing ceremonies by indigenous groups in the Amazon, could help in this fight. This powerful hallucinogen is the active ingredient in ayahuasca, a drink used for millennia by South American shamans.

“Current treatments do not work for a large proportion of people,” explains Professor Ravi Das, co-director of the trial at University College London, to the English daily. When it comes to alcohol addiction, 50% of people relapse within three months and around 60-70% within three years. (…) There is therefore an urgent need for new drugs and new therapeutic approaches. »

In its pure form, DMT is one of the most powerful psychoactive substances found in nature. It can cause out-of-body experiences, hallucinations, and significant visions of colorful geometric landscapes.

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For the study, specialists want to give volunteers a single intravenous dose of the drug, whose effects only last about 15 minutes, while a control group receives a placebo or a non-hallucinogenic drug. The goal is to see if DMT can regenerate the brain’s reward system, which normally pushes drinkers to return to alcohol.

A few volunteers have already started the trial but University College London is currently looking for people with a particular profile: “Regular drinkers aged 21 to 65 and without a formal diagnosis of an alcohol disorder. » Precision all the same: the team of experts particularly emphasizes the need to administer the medication under medical supervision.

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