“It’s not always easy to be a woman.” Behind this euphemism, a posters discussed and commented on dedicated to the health of women in infectiology, and in particular pregnant women.
Two studies have been presented, being interested in respiratory infections in the population of pregnant women. A first Chinese study (Zhang et al., Abstract E0358) was interested in obstetric complications in women infected with the flu virus during their pregnancy, over a period of seven years (2012-2019) by retrospectively comparing 394 infections with more than 21,000 vaccinated women.
If overall, there was no difference in terms of complications between infected and vaccinated women (Figure 1), the authors observed a significant increase in the risk of small weight at birth (or = 1.70 [1.01-2.86]) and prematurity (or = 1.91 [1.18-3.09]) when the infection occurred in the first trimester. Conversely, vaccination was associated with a significant decrease in the risk of cesarean (or = 0.94 [0.90 – 0.98]) or even prematurity (or = 0.69[0.64 – 0.74].
This study confirms the importance of vaccinating pregnant women against flu, from the first quarter. Complex situation as the list of vaccines offered to pregnant women is long 1 (Besides the flu vaccine, the vaccine against COVID-19 A coronavirus disease, sometimes designated COVVID (according to the English acronym from Coronavirus DIEASE) is a disease caused by a coronavirus (VOC). The expression can refer to the following diseases: severe acute respiratory syndrome (SRAS) caused by the SARS-COV virus, the Middle East respiratory syndrome (seas) caused by the MERS-COV virus, 2019 coronavirus disease (COVVI-19) caused by the SARS-COV-2 virus. Vaccination against darling with a tetravalent vaccine (DTCAP), vaccination against VRS …) in a context of complex vaccination acceptability2. In France, vaccination coverage against flu in pregnant women was estimated at 21% between 2019 and 2021, far from the target of 75% vaccination coverage in this population (Vaux S et al, Beh 2023).
Pregnant women and Covid A coronavirus disease, sometimes designated COVVID (according to the English acronym from Coronavirus DIEASE) is a disease caused by a coronavirus (VOC). The expression can refer to the following diseases: severe acute respiratory syndrome (SRAS) caused by the SARS-COV virus, the Middle East respiratory syndrome (seas) caused by the MERS-COV virus, 2019 coronavirus disease (COVVI-19) caused by the SARS-COV-2 virus. long
A second study conducted in Singapore (Tan et al., Abstract E0360) has retrospectively analyzed a cohort of 11,200 women infected with SARS-COV-2 during their pregnancy (and more than 99% of whom had a complete vaccination scheme) compared to 15,200 pregnant women who did not contract the virus and 332,000 having been infected outside a pregnancy period. Pregnant infected women thus had a significantly higher risk of presenting symptoms linked to post-Aigu infection (AHR = 13.39 [10.55-16.98]). The main manifestations observed were neurological. Interestingly, the risk of developing a long covid was increased in 3e trimester of pregnancy (ahr = 4.16[2.38 – 7.30]).
This sur-risk was highlighted whatever the age of the woman at the time of her pregnancy, and therefore independently of the 35-year threshold beyond which a pregnancy is said to be “geriatric” by the specialists of the question. If the long-term consequences of SARS-COV-2 infection are now well known and described, this study has the interest of specifically interested in the particular population of pregnant women in the omicron era.
